Features List

Polynucleotides

  • AT A GLANCE
  • TREATMENT TIME 30 mins
  • PAIN None to mild
  • RESULTS In a few Weeks
  • RESULTS DURATION 6-12 months
  • PRICE From £300
  • What are Polynucleotides?
  • How do Polynucleotides work?
  • How is the treatment administered?
  • Side Effects
  • Before & After Gallery
  • Frequently Asked Questions
Polynucleotides

What are Polynucleotides?

Polynucleotides constitute a component primarily sourced from fish DNA, endowing them with natural, compatible, and biodegradable properties. Dr. Alexa elucidates that polynucleotides serve as a vital stimulus for cells, akin to nourishment or medicine. This stimulation prompts cells to generate collagen and elastin, contributing to the enhancement of the extracellular matrix—a pivotal structural layer in our skin responsible for maintaining a youthful appearance, housing fibrous elements like collagen and elastin.

At times, treatments involving polynucleotides may be categorized as Biostimulators, Biofillers, or Biorevitalisers, contingent on the manufacturer and composition. Regardless of the nomenclature, Dr. Alexa emphasizes that they all share a fundamental anti-aging component: polynucleotides. 

How do Polynucleotides work?

Polynucleotides operate at a cellular and histological level by entering target tissues and influencing gene expression, particularly in processes related to tissue repair and regeneration.

Once introduced into cells, polynucleotides interact with cellular machinery, serving as molecular signals that stimulate fibroblasts—the cells responsible for synthesizing crucial structural proteins like collagen and elastin. This stimulation leads to an increase in collagen production, which enhances the extracellular matrix (ECM), providing structural support to cells.

The improved ECM, in turn, contributes to tissue repair, regeneration, and overall skin rejuvenation. Through their role in modulating gene expression, stimulating collagen synthesis, and enhancing the extracellular matrix, polynucleotides offer a scientific basis for their application in aesthetic and therapeutic treatments, promoting healthier and more resilient skin. Ongoing research aims to refine our understanding of these processes and optimize the effectiveness of polynucleotide-based therapies.

Polynucleotides
Polynucleotides

How is the treatment administered?

Polynucleotide treatments are typically administered through injections, commonly subcutaneously or intradermally, with the specific method tailored to the treatment goals and targeted area. Before the procedure, a consultation with a qualified healthcare or aesthetic professional assesses the individual’s needs and determines the suitability of the treatment.


The skin is prepared by cleansing, and in some cases, a topical anesthetic may be applied to minimize discomfort. Using fine needles, the polynucleotide solution is then injected into the designated tissue to stimulate processes such as collagen production and tissue regeneration. The number of sessions required varies based on factors such as the desired outcomes and the specific product used.

Side effects

Polynucleotide treatments generally have a favorable safety profile, but like any medical or aesthetic procedure, they may be associated with some side effects. Common side effects are usually mild and temporary, including redness, swelling, and bruising at the injection site. These effects typically resolve within a few days as the skin heals.

In rare cases, individuals may experience more significant side effects, such as infection, allergic reactions, or nodules at the injection site. To minimize risks, it’s crucial to have these treatments performed by qualified and experienced healthcare professionals who follow proper hygiene and injection techniques.

Polynucleotides

Before & After Gallery

Frequently
Asked Questions

Polynucleotides are long chains of nucleotides that form the building blocks of nucleic acids, such as DNA and RNA. They play a crucial role in genetic information storage and cellular functions.

Polynucleotides in skin treatments work by stimulating cellular processes, enhancing collagen and elastin production, and improving the extracellular matrix. This leads to tissue repair, regeneration, and overall skin rejuvenation.

The number of sessions varies based on individual goals, the specific product used, and the provider's recommendations. Multiple sessions are often recommended for optimal results.

Yes, polynucleotide treatments have been used for scar reduction. They promote tissue repair and regeneration, improving the appearance of scars over time.

Yes, polynucleotides are often derived from natural sources, such as fish DNA, making them biocompatible and biodegradable.

The duration of effects varies, and maintenance sessions may be recommended for prolonged benefits. Individual factors and the specific treatment contribute to the longevity of results.

Polynucleotide treatments are generally suitable for various skin types, but individual responses may vary. A consultation with a healthcare professional helps determine suitability.

Yes, polynucleotide treatments can be combined with other aesthetic procedures to achieve comprehensive skincare goals. Consultation with a healthcare professional helps plan a personalized approach.

Results vary, but some individuals may notice improvements shortly after the first session. The full effects typically become more apparent with subsequent sessions and as the skin continues to regenerate over time.

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